Propensity and appraisal of biochar performance in removal of oil spills: A comprehensive review.

Recently, the adsorption-based environmental remediation techniques have gained a considerable attention, due to their economic viability and simplicity over other methods. Hence, detailed presentation and analysis were herein focused on describing the role of biochar in oil spill removal. Oil removal by utilizing biochar is assumed as a green-oriented concept.

Congenital hypertrophy of retinal pigment epithelium (CHRPE) in patients with familial adenomatous polyposis (FAP); a polyposis registry experience.

Background: Familial Adenomatous Polyposis (FAP) is an autosomal dominant condition giving rise to multiple adenomatous polyps in the colon which invariably become malignant by the fourth decade. Congenital hypertrophy of retinal pigment epithelium (CHRPE) is one of its extra intestinal manifestations early in childhood seen, present in 90% of FAP population and is easy to detect.

Findings: Patients diagnosed with FAP and at risk first degree family members were screened for CHRPE using a slit lamp and indirect ophthalmoscopy.

Manic fringe inhibits tumor growth by suppressing Notch3 degradation in lung cancer.

Notch signaling plays an essential role in development as well as cancer. We have previously shown that Notch3 is important for lung cancer growth and survival. Notch receptors are activated through the interaction with their ligands, resulting in proteolytic cleavage of the receptors.

Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation.

Background: Pancreas cancer is one of most aggressive human cancers with the survival rate for patients with metastatic pancreas cancer at 5-6 months. The poor survival demonstrates a clear need for better target identification, drug development and new therapeutic strategies. Recent discoveries have shown that the role for Notch pathway is important in both development and cancer.