RSVP Keyboard with Inquiry Preview: mixed performance and user experience with an adaptive, multimodal typing interface combining EEG and switch input.

Objective: The RSVP Keyboard is a non-implantable, event-related potential-based brain-computer interface (BCI) system designed to support communication access for people with severe speech and physical impairments. Here we introduce Inquiry Preview, a new RSVP Keyboard interface incorporating switch input for users with some voluntary motor function, and describe its effects on typing performance and other outcomes.

Approach: Four individuals with disabilities participated in the collaborative design of possible switch input applications for the RSVP Keyboard, leading to the development of Inquiry Preview and a method of fusing switch input with language model and electroencephalography (EEG) evidence for typing.

Clinical and immunological outcomes after randomized trial of baked milk oral immunotherapy for milk allergy.

BACKGROUNDCow's milk (CM) allergy is the most common food allergy in young children. Treatment with oral immunotherapy (OIT) has shown efficacy, but high rates of adverse reactions. The aim of this study was to determine whether baked milk OIT (BMOIT) could reduce adverse reactions while still inducing desensitization, and to identify immunological correlates of successful BMOIT.

Strengthening tobacco control research: key factors impacting policy outcomes and health equity.

In this policy brief, we explore several potential drivers of heterogeneity in policy outcomes that can be examined in tobacco control policy evaluations, expanding the evidence base to contribute to continued, equitable progress in reducing tobacco-related health outcomes. We discuss these factors in the context of a hypothetical evaluation of the impact of smoke-free laws on current smoking and quit attempts in the Tobacco Nation. Despite a similar policy environment within the Tobacco Nation, there is variation in the strength of smoke-free law coverage across states.

Persistent organic pollutants and endogenous sex-related hormones in Hispanic/Latino adults: The Hispanic Community health study/study of Latinos (HCHS/SOL).

Background: Previous studies have demonstrated associations of persistent organic pollutants (POPs) with sex-related hormones; however, findings were inconsistent. Sex-specific impacts and pathways through which adiposity influences associations are not completely understood. We sought to evaluate sex-specific associations of POPs serum concentration with sex-related hormones and to explore pathways through which adiposity may modify associations.

Targets of influenza human T-cell response are mostly conserved in H5N1.

Frequent recent spillovers of subtype H5N1 clade 2.3.4.