Publications by authors named "B Gurer"
Article Synopsis
- In a study involving rats, researchers tested the effects of esomeprazole on excessive scarring after laminectomy surgery.
- The experiment included three groups: a control group with no treatment, a local esomeprazole group with topical application, and a systemic esomeprazole group receiving the drug intraperitoneally.
- Results showed that esomeprazole significantly reduced macroscopic and microscopic epidural fibrosis compared to the control group, indicating its potential benefit in preventing scar formation after surgery.
Aim: To examine the effects of amantadine, a drug with neuroprotective and anti-inflammatory activities on oxidative stress, tissue necrosis, apoptosis, and neurological recovery in an experimental rabbit spinal cord ischemia-reperfusion injury (SCIRI) model.
Material And Methods: A total of 32 rabbits were randomized into five groups: control, ischemia, vehicle, methylprednisolone (MP), and amantadine (AMT) (n=8/each). At 24th-hour neurological examination was performed, spinal cord tissues were collected, and biochemical and histopathological examinations were performed.
Background: Laminectomy is a widely employed surgical procedure for the treatment of spinal stenosis, but it may lead to epidural fibrosis (EF) and failed back surgery syndrome. Cinnamaldehyde, a phenylpropanoid found in cinnamon, has demonstrated antioxidant and anti-inflammatory properties. In the present study, we hypothesized that topical application and systemic administration of cinnamaldehyde could be helpful in the prevention of EF in a rat laminectomy model.
View Article and Find Full Text PDFThe role of ASA score and Charlson comorbidity index in predicting in-hospital mortality in geriatric hip fracture patients.
Eur Rev Med Pharmacol Sci
August 2023
Objective: We aimed to determine the role of American Society of Anesthesiologists (ASA) score and Charlson Comorbidity Index (CCI) in determining in-hospital mortality and other factors associated with mortality in patients over 65 years of age who underwent surgery for hip fracture during our study, including the COVID-19 process.
Patients And Methods: Between January 1st, 2020, and December 31st, 2021, 200 patients over 65 years of age who underwent hemiarthroplasty or internal fixation for hip fracture after low-energy trauma were retrospectively evaluated.
Results: Of the 200 patients included in the study, 130 were female and 70 were male.