Publications by authors named "B Guinn"
Article Synopsis
- Ovarian torsion (OT) is a rare but critical gynecological emergency that requires quick diagnosis and management, leading researchers to explore non-invasive biomarkers for detection.
- A systematic review of literature from five databases examined studies on biomarkers related to OT, resulting in the inclusion of 23 articles that reported on both animal and human research.
- Key biomarkers identified included ischemia-modified albumin (IMA), serum D-dimer (s-DD), and interleukin-6 (IL-6), with specificities reaching 93.3% and sensitivities ranging from 16.4% to 92.3%, indicating their potential for early identification of OT in patients.
Acute myeloid leukemia (AML) is a malignant disease of the blood and bone marrow that is characterized by uncontrolled clonal proliferation of abnormal myeloid progenitor cells. Nucleophosmin 1 (NPM1) gene mutations are the most common genetic abnormality in AML, detectable in blast cells from about one-third of adults with AML. AML NPM1 is recognized as a separate entity in the World Health Organization classification of AML.
View Article and Find Full Text PDFObjectives: To examine disparities in attendance rates at cancer screening services between transgender and gender-diverse (TGD) people in comparison with their cisgender (CG) counterparts, and to determine whether these differences were based on the anatomical organ screened.
Design: Systematic review and meta-analysis.
Data Sources: PubMed, EMBASE (via Ovid), CINAHL Complete (via EBSCO) and Cochrane Library from inception to 30 September 2023.
Purpose: Cancer registries offer an avenue to identify cancer clusters across large populations and efficiently examine potential environmental harms affecting cancer. The role of known metal carcinogens (i.e.
View Article and Find Full Text PDFCasDinG is an ATP-dependent 5'-3' DNA helicase essential for bacterial Type IV-A1 CRISPR associated immunity. CasDinG contains an essential N-terminal domain predicted to bind DNA. To better understand the role of the N-terminal domain, we attempted to co-crystallize CasDinG with DNA substrates.
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