Publications by authors named "B Guida"

Background/objectives: One of the main culprits of the obesity epidemic is the obesogenic food environment, which promotes the consumption of ultra-processed foods (UPFs) that are highly palatable, have low nutritional quality and a high caloric impact and are economical and ready to use. This monocentric retrospective study explored the association between UPFs, obesity and adiposity measurements among adults living with obesity in Southern Italy.

Methods: According to their Body Mass Index (BMI) values, 175 participants (63M) were recruited and stratified into three groups.

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  • - The study examined the relationship between skeletal muscle mass and plasma lipid levels in healthy young adults aged 18-45, analyzing data from 450 subjects over a 15-year period.
  • - Researchers measured skeletal muscle mass using bioelectrical impedance analysis and compared lipid profiles, revealing that overweight and obese individuals had higher total cholesterol, LDL cholesterol, and triglycerides but lower HDL cholesterol than those of normal weight.
  • - The findings indicated that in obese females, lower skeletal muscle mass correlated with reduced HDL cholesterol, implying that muscle mass changes in obesity may negatively impact lipid profiles, particularly HDL levels.
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  • The rising prevalence of chronic kidney disease (CKD) among the elderly poses challenges due to conflicting dietary recommendations: low-protein diets are advised for CKD while higher protein intake is suggested for preventing malnutrition in older adults.
  • This study investigates the effects of a low-protein adequate energy (LPAE) diet on nutritional status and metabolic issues in elderly CKD patients (stages 3-5) over six months.
  • Results indicate that compliant patients on the LPAE diet saw improvements in body composition and metabolic parameters without increased malnutrition risk, highlighting its potential as a safe dietary approach for this population.
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Purpose Of Review: The goal of the present review is to address the main adiposity-related alterations in Polycystic Ovary Syndrome (PCOS) focusing on hypothalamic-pituitary-ovarian (H-P-O) axis and to provide an overview of nutraceutical and pharmacological therapeutic strategies.

Recent Findings: Female reproduction is a complex and delicate interplay between neuroendocrine signals involving the H-P-O axis. Elements that disrupt the balance of these interactions can lead to metabolic and reproductive disorders, such as PCOS.

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Obesity is a risk factor for several diseases present worldwide. Currently, dietary changes and physical activity are considered the most effective treatment to reduce obesity and its associated comorbidities. To promote weight loss, hypocaloric diets can be supported by nutraceuticals.

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