Role of gamma knife radiosurgery in the management of pituitary adenomas and craniopharyngiomas.

Introduction: Radical microsurgical removal of pituitary adenomas (PAs) and craniopharyngiomas (CPHs) is often difficult. In such cases radiosurgery can be used as a second-line treatment option.

Materials And Methods: Our series included 436 PAs and 164 CPHs.

[Excellent response to external radiotherapy of a primary synovial sarcoma of the parotid gland].

Le synovialosarcome de la parotide est rare, peu de cas ont été rapportés dans la littérature. Nous rapportons l’observation d’une patiente âgée de 40 ans qui a présenté d’un synovialosarcome primitif de la parotide, dont le traitement a associé une chirurgie suivie d’une radiothérapie adjuvante. L’évolution a été marquée par un bon contrôle locorégional avec un recul de 6 ans.

Metastatic ameloblastoma responding to combination chemotherapy: case report and review of the literature.

Background: Ameloblastoma is a rare benign odontogenic tumor with locally aggressive behavior and a high recurrence rate. When metastases occur, which are uncommon, lungs constitute the most frequent site involved. Malignant ameloblastomas are different from ameloblastic carcinomas.

Genetic testing and first presymptomatic diagnosis in Moroccan families at high risk for breast/ovarian cancer.

Germline mutations in the BRCA1 and BRCA2 genes highly predispose to breast and ovarian cancers and are responsible for a substantial proportion of familial breast and ovarian cancers. No female individuals from families from Morocco affected by breast cancer with mutations of these genes have previously been reported, and clinicians in Morocco are unaccustomed to dealing with healthy female individuals carrying mutations in the BRCA genes. This study aimed to report the initial experience of a group of Moroccan investigators carrying out predictive genetic testing to detect a known familial mutation in healthy Moroccan females with a high risk of developing breast cancer and to introduce supervision of these asymptomatic female carriers as a new approach in the prevention and early diagnosis of breast and ovarian cancers in Morocco.