Publications by authors named "B Gontijo"

Article Synopsis
  • Major depressive disorder (MDD) impacts over 300 million people worldwide and has various causes, with the CYP2C19 enzyme affecting how some antidepressants are metabolized.
  • A systematic review followed specific protocols and found only nine relevant studies from 240 articles that met inclusion criteria regarding gene variant frequencies and their effects on MDD.
  • While some genetic variants showed associations with MDD symptoms and treatment responses, results were inconsistent, indicating a need for more research to better understand these genetic influences on depression and improve treatment options.
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Major Depressive Disorder (MDD) is a disabling and particularly persistent mental disorder that is considered to be a priority public health problem. The active human dopamine transporter (DAT), which is encoded by the gene, regulates the dopamine concentration in the synaptic cleft. In this sense, this neurotransmitter is primordial in modulating human emotions.

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Tracking hip and thigh axial rotation has limited accuracy due to the large soft tissue artifact. We proposed a tracking-markers cluster anchored to the prominent distal part of the iliotibial band (ITB) to improve thigh tracking. We investigated if the ITB cluster improves accuracy compared with a traditionally used thigh cluster.

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The anomalous origin of one pulmonary artery from the ascending aorta is a rare congenital heart disease, generally diagnosed based on the clinical information and on echocardiographic and computed tomography angiography findings. Here we report two neonates successfully treated with surgery early in life.

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