Spatiotemporal analysis of mosquito-borne infections and mosquito vectors in mainland Portugal.

Background: The incidence of mosquito-borne infections has increased worldwide. Mainland Portugal's characteristics might favour the (re)emergence of mosquito-borne diseases. This study aimed to characterize the spatial distribution of vectors and notification rates of imported cases of mosquito-borne infections in mainland Portugal and demarcate the areas where these geographies overlap.

Developing Topics.

Background: Lewy bodies (LB), the main hallmark of Parkinson's disease (PD), are a frequent co-pathology in Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). The varying extents of LB pathology in these disorders can influence disease progression and severity. Consequently, understanding LB impact on the proteomic profile of these diseases is crucial, potentially leading to identifyng novel blood biomarkers related to this pathology which are urgently needed.

Developing Topics.

Background: Synaptic dysfunction is a prominent feature in neurodegenerative disorders, associating with cognition. In contrast to most synaptic proteins assessed in cerebrospinal fluid (CSF), Neuronal pentraxin 2 (NPTX2), essential for synaptic plasticity, exhibits downregulation neurodegenerative disorders through mass spectrometry (MS) methods. While MS-based assays hold promise, their constraints hinder widespread clinical adoption.

Seroconversion and seroreversion rates of anti-Strongyloides IgG in rural areas of the Amazon: a population-based panel study.

Using a panel study design, we aimed to estimate the seroconversion and seroreversion rates of anti-Strongyloides IgG antibodies from surveys carried out 11 months apart in a rural community in the Amazon Basin in Brazil. We used enzyme immunoassays to measure anti-Strongyloides IgG antibodies in 325 baseline plasma samples and 224 others that were collected 11 months later from residents in the agricultural settlement of Granada, Acre State. We observed anti-Strongyloides IgG antibodies in 21.

Information systems project success surveys - Insights from the last 30 years.

Information Systems (IS) projects have a long history of negative reputation regarding their success. However, studies that report the success of IS projects are generally focused on software development (which is only one of the many types of IS projects). Furthermore, practically no research compares the success achieved in the different types of IS projects and projects from other areas.