Publications by authors named "B Godard"
Introduction: Researchers, clinicians and patients are turning to new innovations in research and clinical practice to further their knowledge in the genetic domain and improve diagnostics or treatment. However, with increased knowledge in genetics, societal issues may arise. Being conscious of these issues is crucial in order to implement standardized and efficient testing on a wider scale that is accessible to a greater number of individuals while simultaneously returning test results, including incidental findings, in a timely manner.
View Article and Find Full Text PDFVentral tail bending, which is transient but pronounced, is found in many chordate embryos and constitutes an interesting model of how tissue interactions control embryo shape. Here, we identify one key upstream regulator of ventral tail bending in embryos of the ascidian Ciona. We show that during the early tailbud stages, ventral epidermal cells exhibit a boat-shaped morphology (boat cell) with a narrow apical surface where phosphorylated myosin light chain (pMLC) accumulates.
View Article and Find Full Text PDFArticle Synopsis
- Pluripotent cells are critical for development in eutherian embryos, transitioning from a naïve state to a primed state during gastrulation.
- The study traces the evolution of the Pou5 gene family, especially the OCT4 protein, which is key for maintaining pluripotency, highlighting its emergence in early jawed vertebrates.
- The research reveals that gene duplication led to the creation of two versions of Pou5 (Pou5f1 and Pou5f3), which have specialized roles in supporting different stages of pluripotency, thus enhancing their functions in cell self-renewal and differentiation.
The objective of this study was to describe and assess the quality of the direct-to-consumer medical teleconsultation landscape in three Canadian provinces. An environmental scan of primary care teleconsultation platforms was conducted in January 2022 to identify medical teleconsultation platforms in Quebec (Qc), Ontario, and British Columbia (BC). The quality of each teleconsultation platform was assessed using a modified version of the HONcode principles.
View Article and Find Full Text PDFRespective Impact of Day and Night Bed Baths on Critical Care Patients.
Dimens Crit Care Nurs
February 2022
Background: Despite data supporting the reduction of interactions with patients during nighttime, bed bathing is sometimes performed within this period in sedated patients unable to manage their own hygiene care.
Objectives: To compare patient physiologic variables and adverse effect incidence between night and day bed baths.
Methods: This was a single-center prospective observational study in a 12-bed intensive care unit during 2 months.