Potential consequences of the Fukushima accident for off-site nuclear emergency management: a case study for Germany.

The Fukushima accident led to high radionuclide releases into the atmosphere for more than 3 weeks. This situation has not been assumed when the concepts of nuclear emergency preparedness were developed internationally. The results of simulations studying potential implications of Fukushima-like source terms on nuclear emergency preparedness are presented.

A two-step concept to derive a consistent set of intervention levels for radiation emergency planning and to translate international recommendations into practical guidance.

A two-step concept is proposed in order to derive a consistent set of intervention levels for early (sheltering, evacuation) and late (relocation/resettlement, returning) protective actions that have to be considered in radiation emergency planning. In the first step, the dose ratios of the projected effective doses have to be calculated for four defined time periods, which correspond with the integration times for sheltering and relocation. In the second step, it is necessary to adopt an intervention level for one protective action or a more general reference level for a certain time period as, for example, the reference level recommended by the International Commission on Radiological Protection (ICRP) Publication 103 in 2007.

Non-clathrin-coat protein alpha is a conserved subunit of coatomer and in Saccharomyces cerevisiae is essential for growth.

To complete the molecular characterization of coatomer, the preformed cytosolic complex that is involved in the formation of biosynthetic transport vesicles, we have cloned and characterized the gene for non-clathrin-coat protein alpha (alpha-COP) from Saccharomyces cerevisiae. The derived protein, molecular weight of 135,500, contains four WD-40 repeated motifs (Trp/Asp-containing motifs of approximately 40 amino acids). Disruption of the yeast alpha-COP gene is lethal.

Comparison of gallium-67 versus indium-111 monoclonal antibody (96.5, ZME-018) in detection of human melanoma in athymic mice.

We compared the biodistribution of two radiolabeled, whole, tumor selective monoclonal antibodies [( 111In]96.5, [111In]ZME-018) to 67Ga in nude mice bearing a human melanoma known to express p97 antigen. Localization of gallium was determined 48 hr following i.