[Complex surgical treatment of patients with necrotic soft tissue infections].

Objective: To develop an optimal algorithm for complex treatment of patients with necrotic soft tissue infections (NSTI).

Material And Methods: The study included 114 patients with NSTI who were treated between 2016 and 2021. We analyzed treatment outcomes in 2 groups: retrospective (=43) with traditional approaches to purulent surgery (drainage of necrotic foci, local therapy with iodophores and water-soluble ointments, antibacterial and detoxification therapy, delayed skin grafting) and prospective (=71) with active surgical treatment and modern algorithm based on a differentiated approach and high-tech methods (vacuum therapy, hydrosurgical treatment of wounds, early skin grafting and extracorporeal hemocorrection).

[New approaches in conservative treatment of acute adhesive small bowel obstruction].

Objective: To improve the outcomes of therapy of acute adhesive small bowel obstruction via development of a comprehensive management including CT, deep endoscopy-assisted nasointestinal drainage of small bowel with injection of a water-soluble contrast.

Material And Methods: There were 128 patients with acute adhesive small bowel obstruction for the period from 2015 to 2018. The study included 2 groups of patients depending on therapeutic approach and duration of treatment.

The effect of porphyrin supramolecular structure on singlet oxygen photogeneration.

This work is to show that activity of porphyrins in singlet oxygen generation (SOG) is determined not only by their molecular structure but also by supramolecular structure of porphyrin containing systems. This is demonstrated by results of studies of SOG in the gas phase by vacuum deposited tetraphenylporphyrin (TPP) layers under photoexcitation conditions. The structure of the layers was studied by atomic force microscopy (AFM), TEM in diffraction regime (TED) and by the flicker-noise spectroscopy (FNS) method.