The feasibility and safety of robotic-assisted salvage radical cystectomy.

Objectives: To evaluate the feasibility and safety of robotic-assisted salvage radical cystectomy (RA-SRC).

Materials And Methods: We retrospectively searched the prospectively collected surgical database of two highly experienced robotic urological surgeons for cases of RA-SRC, defined as RARC performed post-previous pelvic RT for palliative or oncologic treatment purposes. Collected data included demographic and clinical information and outcome measures including operative course, hospital stay and complications.

Risk Factors and Predictors for Persistent Dyspnea Post-COVID-19: A Systematic Review.

The most frequently reported post-coronavirus disease of 2019 (COVID-19) symptoms include shortness of breath, fatigue, and cognitive disturbances, with reports of persistent dyspnea ranging between 26% and 41%. There is an urgent need to understand the risk factors and predictors for persistent COVID-19 dyspnea in individuals at all levels of COVID-19 illness severity, to enable the implementation of targeted interventions for those likely to be most affected with persistent dyspnea. Thus, the purpose of this systematic review is to explore the risk factors and predictors that are associated with persistent dyspnea in the post-COVID-19 population.

Affirmative Action-A Crack in the Door to Higher Education.

The impact of the Supreme Court of the United States ruling against race-conscious admissions extends beyond college admissions to professional schools. Based partially on the idea that enough time had elapsed for achievement of the stated goals of affirmative action, the court ruled race-conscious admissions are unconstitutional under the 14th Amendment's Equal Protection Clause. The ruling left a crack in the door to higher education, however, allowing students to write an essay showing how race or ethnicity affected their lives.

Deciphering the Topology of Sitagliptin Using an Integrated Approach.

Determining the structure of sitagliptin is crucial for ensuring its effectiveness and safety as a DPP-4 inhibitor used to treat type 2 diabetes. Accurate structure determination is vital for both drug development and maintaining quality control in manufacturing. This study integrates the advanced techniques of solid-state nuclear magnetic resonance (NMR) spectroscopy, three-dimensional (3D) electron diffraction, and density functional theory (DFT) calculations to investigate the structural intricacies of sitagliptin.

A new approach for assessing the radioecological risk associated with the legacy discharge of oil derived natural radioactivity in the UK North Sea.

Although oil and gas (O&G) derived produced waters and drill cuttings are known to contain enhanced levels of naturally occurring radium-228 (Ra) and radium-226 (Ra), most relevant ecological impact assessments have excluded radiological hazards and focus on other important contaminants, such as hydrocarbons and metals. Also, due to restricted access to the delimiting safety zone around operational O&G platforms, the few previous radioecological risk assessment studies have been conducted using seawater samples collected far from the main discharge point and applying default dilution and transfer factors to estimate concentrations of contaminants in biota. In this case study, sediment cores were collected close to a former O&G platform, Northwest Hutton (NWH), that used to be in the UK North Sea (61.