Misoprostol induces relaxation of human corpus cavernosum smooth muscle: comparison to prostaglandin E1.

Prostaglandin E1 (PGE1) relaxes trabecular smooth muscle by interacting with specific G-protein coupled receptors on human corpus cavernosum smooth muscle and increasing intracellular synthesis of cAMP. Misoprostol (Cytotec), is an oral prostaglandin E analogue. The purpose of this study was to compare the functional activity of misoprostol with PGE1 in human corpus cavernosum and cultured human corpus cavernosum smooth muscle cells.

Ureteral tailoring in situ: a practical approach to persistent reflux in the dilated reimplanted ureter.

Purpose: We evaluated a new simplified technique for secondary surgical correction of persistent reflux in a reimplanted dilated ureter.

Materials And Methods: Four patients a median of 3 years old with recurrent vesicoureteral reflux after initial reimplantation of ureters greater than 9 mm. in diameter underwent in situ excisional ureteral tailoring.

Renal colic during pregnancy: a case for conservative treatment.

Purpose: We defined the merits of early evaluation and conservative treatment of pregnant patients admitted with renal colic.

Materials And Methods: We retrospectively evaluated 72 pregnancies in 70 patients who were hospitalized with the diagnosis of renal colic between 1984 and 1995. Urinalysis was performed in every case.

Obstructive anuria and dermatomyositis: a unique association.

This case is the first reported presentation of obstructive anuria due to extrinsic ureteral compression in a patient with dermatomyositis. Further evaluation revealed disseminated sigmoid colon adenocarcinoma. Conservative treatment of ureteral obstruction by internal double-J stents achieved appropriate palliation.