Publications by authors named "B G Mirembe"
Article Synopsis
- Product adherence significantly impacts the accurate evaluation of HIV-1 prevention methods like the dapivirine vaginal ring, with varying levels of adherence leading to biased efficacy estimates.* -
- In the MTN-020/ASPIRE trial, per-protocol analyses indicated a 30.8% efficacy, while those with the highest adherence showed an efficacy of 53.6% when analyzing drug release from the ring.* -
- Advanced statistical methods, such as principal stratification and marginal structural models, enhance our understanding of HIV-1 prevention effectiveness in clinical trials by adjusting for adherence levels.*
Article Synopsis
- * The WHO published the first COVID-19 Weekly Epidemiological Update on August 17, 2020, and continued until the final edition on September 1, 2023, after which updates transitioned to a comprehensive format every 4 weeks.
- * The article reviews the WEU's data collection and publication process, its global impact, and offers recommendations to improve collaboration and information sharing for future health crises.
Article Synopsis
- COVID-19 is caused by a virus with no vaccines or treatments available during the study, necessitating the assessment of knowledge and adherence to public health measures among the Ugandan population.
- A cross-sectional study in Uganda involved face-to-face interviews and questionnaires to gauge household knowledge, attitudes, and adherence to COVID-19 prevention strategies.
- Findings showed that while knowledge levels were adequate (72.2%), adherence rates were moderate (63.7%), and positive attitudes (57.8%) were significant; higher knowledge correlated with better attitudes and adherence to prevention measures.
Surveillance for variants of SARS-CoV-2 to inform risk assessments.
Homa Attar Cohen Samuel Mesfin Juniorcaius Ikejezie Zyleen Kassamali Finlay Campbell Bernadette Basuta Mirembe
Bull World Health Organ
November 2023
Article Synopsis
- The COVID-19 pandemic has seen the emergence of numerous SARS-CoV-2 variants, impacting global health through increased infections and hospitalizations.
- Early detection and effective surveillance of these variants are crucial for understanding their health risks and guiding public health responses.
- The article outlines past variants, their genetic evolution, and the importance of integrating genomic data with epidemiological insights for ongoing and future public health initiatives.
Article Synopsis
- The 2022-2023 mpox outbreak mainly impacted adult men, with only 1.3% of cases occurring in children and teens under 18.
- In the analyzed data, there was only one ICU admission for children and no recorded deaths in that age group.
- Different age groups experienced various transmission routes and clinical symptoms during the outbreak.