monitoring of mechanochemical MOF formation by NMR relaxation time correlation.

In this paper, we present a new approach to monitoring mechanochemical transformations, based on a magnetic resonance (MR) method in which relaxation time correlation maps are used to track the formation of the popular metal-organic framework (MOF) materials Zn-MOF-74 and ZIF-8. The two-dimensional (2D) relaxation correlation measurement employed yields a spectrum which visually and analytically identifies different H environments in the sample of interest. The measurement is well-suited to analyzing solid mixtures, and liquids, in complex systems.

The Global Characterisation of a Drug-Dendrimer Conjugate - PEGylated poly-lysine Dendrimer.

The recent emergence of drug-dendrimer conjugates within pharmaceutical industry research and development introduces a range of challenges for analytical and measurement science. These molecules are very high molecular weight (100-200kDa) with a significant degree of structural complexity. The characteristics and quality attributes that require understanding and definition, and impact efficacy and safety, are diverse.

Magnetic resonance T-T* and T-T* relaxation correlation measurements in solid-like materials with non-exponential decays.

Magnetic resonance T-T* relaxation correlation is a newly emerging and powerful tool to study the structure and dynamics of materials. However, the T-T* of solid-like materials may consist of a linear combination of exponential decays and non-exponential decays, and the traditional methods for processing T-T data would be not applicable. In this paper, a method of processing T-T* data with non-exponential decays was proposed.

T-T* relaxation correlation measurements.

The majority of low field Magnetic Resonance (MR) analyses rely on T lifetime measurements. Modification of the T measurement to include a T dimension has made the T-T measurement a very powerful analytical technique. The T-T measurement is uniquely well suited to characterization of different spin populations in porous materials, such as fluid bearing reservoir rocks, and in soft biopolymer materials, for example foods.