Native vegetation degradation impacts soil communities and their functions. However, these impacts are often studied by comparing soil biotic attributes across qualitatively defined, discrete degradation levels within a single plant community at a specific location. Direct quantification of the relationships between vegetation and soil attributes across continuous degradation gradients and at larger scales is rare but holds greater potential to reveal robust patterns in aboveground-belowground linkages that may apply across different plant communities.
View Article and Find Full Text PDFCoastal populations are susceptible to relative sea-level (RSL) rise and accurate local projections are necessary for coastal adaptation. Local RSL rise may deviate from global mean sea-level rise because of processes such as geoid change, glacial isostatic adjustment (GIA), and vertical land motion (VLM). Amongst all factors, the VLM is often inadequately estimated.
View Article and Find Full Text PDFGemtuzumab ozogamicin (GO) is a CD33-targeting antibody-drug conjugate approved for the treatment of CD33-positive de novo and relapsed and refractory acute myeloid leukemia (AML). Subset analyses have demonstrated improved clinical outcomes in patients with favorable-risk disease. It is unclear whether the addition of GO to cytarabine and anthracycline chemotherapy (7+3) improves clinical outcomes compared with other conventional regimens for AML.
View Article and Find Full Text PDFUnlabelled: AbstractBackground: Clinical ethics consults are sometimes requested for patients who lack capacity and do not assent to discharge recommendations, particularly those with neurocognitive or psychiatric disorders desiring home discharge. Balancing the risks and benefits of overriding patient preferences involves considering dignity, values, clinical information, and available resources. Outcomes of such consultations lack characterization in the literature.
View Article and Find Full Text PDF