Publications by authors named "B G Callahan"
A modified enzyme fragment complementation assay has been designed and validated as a turn-on biosensor for nucleic acid detection in dilute aqueous solution. The assay is target sequence-agonistic and uses fragments of NanoBiT, the split luciferase reporter enzyme, that are esterified enzymatically at their C-termini to steramers, sterol-linked oligonucleotides. The Drosophila hedgehog autoprocessing domain, DHhC, serves as the self-cleaving enzyme for the NanoBiT-steramer bioconjugations.
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- - The Dépistage Cognitif de Québec (DCQ) was created to detect atypical dementia, addressing the lack of specific cognitive screening tools and reducing delays in diagnosis and care.
- - A study in Canada and the U.S. involving 260 English-speaking participants validated the English version of the DCQ, showing strong correlations with other cognitive assessments and high reliability across testing conditions.
- - The English DCQ effectively identifies various atypical dementias, making it a quick, 20-minute alternative to comprehensive neuropsychological tests, with standardized scores based on age and education levels.
Article Synopsis
- * Researchers conducted a retrospective case-control study and utilized multivariable regression to find significant risk factors, resulting in a nomogram for prediction.
- * Key findings highlighted that specific medications like heparin and certain blood product transfusions were significant risk factors for developing ACS, with the proposed risk calculator aiding in identifying high-risk patients.
Objective: To identify direct and indirect associations between PCEs and social support to emotion regulation outcomes in adults with ADHD.
Method: Adults with ADHD ( = 81) reported PCEs, current social support, and emotion regulation. Conditional effects modeling examined the direct and indirect relationships between PCEs and emotion dysregulation through social support.
Salmonella enterica Serovar Typhimurium (Salmonella) and its bacteriophage P22 are a model system for the study of horizontal gene transfer by generalized transduction. Typically, the P22 DNA packaging machinery initiates packaging when a short sequence of DNA, known as the pac site, is recognized on the P22 genome. However, sequences similar to the pac site in the host genome, called pseudo-pac sites, lead to erroneous packaging and subsequent generalized transduction of Salmonella DNA.
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