Gait ecological assessment in persons with Parkinson's disease engaged in a synchronized musical rehabilitation program.

Data on gait parameters during real-life activities and home rehabilitation programs for Persons with Parkinson's disease (PwPDs) are scarce. Although cueing has been shown to improve their gait in laboratory conditions, few studies have applied this technique in at-home rehabilitation programs. Our study aimed to explore the use of a real-time synchronized beat-step music program for at-home rehabilitation.

Negative emotions disrupt intentional synchronization during group sensorimotor interaction.

Emotions play a fundamental role in human interactions and trigger responses in physiological, psychological, and behavioral modalities. Interpersonal coordination often entails attunement between individuals in various modalities. Previous research has elucidated the mechanisms of interpersonal synchronization and the emotions aroused by joint action: cardiac activity aligns in disputing marital couples, spectators share enjoyment in observing live dance performances, and joint finger-tapping evokes positive emotions.

Coordination Rigidity in the Gait, Posture, and Speech of Persons with Parkinson's Disease.

Parkinson's disease (PD) is associated with reduced coordination abilities. These can result either in random or rigid patterns of movement. The latter, described here as coordination rigidity (CR), have been studied less often.

Impact of emotion-laden acoustic stimuli on group synchronisation performance.

The ability to synchronise with other people is a core socio-motor competence acquired during human development. In this study we aimed to understand the impact of individual emotional arousal on joint action performance. We asked 15 mixed-gender groups (of 4 individuals each) to participate in a digital, four-way movement synchronisation task.

Tocilizumab Evaluation in HLA-Desensitization before Kidney Transplantation as an Add-On Therapy to Apheresis: The TETRA Study.

Background: Desensitization strategies improve access to transplantation in highly sensitized kidney transplant candidates. Tocilizumab could be a valuable addition to more traditional desensitization regimens. We investigated the effect of tocilizumab as an add-on therapy to our standard of care (SoC) desensitization strategy based on rituximab and apheresis.