Publications by authors named "B Froehlich"

Purpose: Musculoskeletal sarcomas are a rare group of malignant neoplasms, accounting for approximately 12 % of all malignant neoplasms among children. Childhood cancer outcomes vary between developed and developing countries due to financial and educational inequalities. Telemedicine programs have a huge impact on the quality of cancer care, helping to optimize resources for better cancer care in a resource-limited setting.

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Virtual Reality (VR) has become an important tool for conducting behavioral studies in realistic, reproducible environments. In this paper, we present ISA, an Immersive Study Analyzer system designed for the comprehensive analysis of social VR studies. For in-depth analysis of participant behavior, ISA records all user actions, speech, and the contextual environment of social VR studies.

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Article Synopsis
  • Capivasertib is an FDA-approved AKT inhibitor used with fulvestrant for treating HR+, HER2-negative breast cancer patients with specific PI3K pathway mutations, showing less than 30% response rates in early trials.
  • In a study analyzing 16 patient tumors, differences in protein levels were observed between those who benefited from capivasertib treatment and those who did not, with findings indicating that higher translational activity correlates with resistance to the drug.
  • The results suggest that profiling protein concentrations could help refine patient selection for capivasertib therapy, improving outcomes even in genetically preselected patients.
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Collaborative work in social virtual reality often requires an interplay of loosely coupled collaboration from different virtual locations and tightly coupled face-to-face collaboration. Without appropriate system mediation, however, transitioning between these phases requires high navigation and coordination efforts. In this paper, we present an interaction system that allows collaborators in virtual reality to seamlessly switch between different collaboration models known from related work.

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Most prior teleportation techniques in virtual reality are bound to target positions in the vicinity of selectable scene objects. In this paper, we present three adaptations of the classic teleportation metaphor that enable the user to travel to mid-air targets as well. Inspired by related work on the combination of teleports with virtual rotations, our three techniques differ in the extent to which elevation changes are integrated into the conventional target selection process.

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