Publications by authors named "B Frauscher"

Introduction: Precise localization of the epileptogenic zone is critical for successful epilepsy surgery. However, imbalanced datasets in terms of epileptic vs. normal electrode contacts and a lack of standardized evaluation guidelines hinder the consistent evaluation of automatic machine learning localization models.

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In drug-resistant focal epilepsy, planning surgical resection may involve presurgical intracranial EEG recordings (iEEG) to detect seizures and other iEEG patterns to improve postsurgical seizure outcome. We hypothesized that resection of tissue generating interictal high frequency oscillations (HFOs, 80-500 Hz) in the iEEG predicts surgical outcome. Eight international epilepsy centres recorded iEEG during the patients' pre-surgical evaluation.

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This scientific commentary refers to 'The sixth sense: how much does interictal intracranial EEG add to determining the focality of epileptic networks?', by Gallagher . (https://doi.org/10.

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Article Synopsis
  • ! Drug-resistant temporal lobe epilepsy (TLE) is linked with damage in the hippocampus, but research is starting to view it as a wider network issue rather than just localized pathology. * ! A study involving 94 patients assessed the relationship between the brain's functional networks and areas of hippocampal atrophy, revealing two distinct brain networks connected to those atrophied areas. * ! The findings highlight that one network correlates positively with certain brain regions (temporolimbic, medial prefrontal, parietal), while another shows negative correlations with frontoparietal regions, suggesting complex interactions in TLE beyond the hippocampus. *
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We present two unique cases of sleep-related hypermotor epilepsy (SHE) originating from the occipital lobe. Patients with sleep-related seizures and drug-resistant occipital lobe epilepsy were identified from the ANPHY lab stereo-electroencephalography (SEEG) research database at the Duke Comprehensive Epilepsy Center. We identified two young females with frequent sleep-related focal seizures and occasional focal to bilateral tonic clonic seizures characterized by hypermotor movements.

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