Publications by authors named "B F Spiekermann"
Article Synopsis
- * Researchers used high-throughput mutagenesis and mathematical modeling to identify around 200 mutations that influence CD19 splicing, potentially leading to resistance against CART-19 treatment.
- * The study also discovered nearly 100 new splice isoforms that produce likely non-functional CD19 proteins and pinpointed key regulatory elements and RNA-binding proteins (like PTBP1 and SF3B4) that affect CD19 splicing, offering valuable insights for future predictive biomarkers for CART-19 therapy.
Unlabelled: In this prospective, randomized, placebo-controlled study, we (1) determined whether 0.625 mg of IV droperidol given 30 min before emergence from general anesthesia reduces the incidence of immediate and delayed postoperative nausea and vomiting (PONV) in a general surgical adult patient population, and (2) compared the efficacy of droperidol, ondansetron, and promethazine for the rescue treatment of PONV. One hundred fifty adult patients receiving general anesthesia for >2 h received either droperidol (0.
View Article and Find Full Text PDFAirway obstruction after anterior cervical discectomy and fusion (ACDF) is a potentially life-threatening postoperative complication. We experienced a case of airway obstruction after an ACDF attributable to the rigid cervical collar used in the patient's postoperative care, which has not been reported previously.
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