Publications by authors named "B F Sklar"
Background: In Ontario, Canada, province-wide initiatives supporting safer opioid prescribing in primary care include voluntary audit and feedback reports and academic detailing. In this process evaluation, we aimed to determine the fidelity of delivery and receipt of the interventions, the observed change strategies used by physicians, potential mechanisms of action, and how complementary the initiatives can be to each other.
Method: Semi-structured interviews were conducted with academic detailers and with physicians who received both interventions.
Background: The impact of social frailty on older adults is profound including mortality risk, functional decline, falls, and disability. However, effective strategies that respond to the needs of socially frail older adults are lacking and few studies have unpacked how social determinants operate or how interventions can be adapted during periods requiring social distancing and isolation such as the COVID-19 pandemic. To address these gaps, we conducted a scoping review using JBI methodology to identify interventions that have the best potential to help socially frail older adults (age ≥65 years).
View Article and Find Full Text PDFInvolvement of individuals with lived experience, also called "patient partners", is a key element within implementation science, the study of how to put evidence into practice. While conducting a 4-year implementation study focused on improving physician management of opioid prescribing, our research team worked closely with Lived Experience Advisors (LEAs). LEAs were involved throughout the study, including developing patient-facing recruitment material, informing the analysis of results, and as a regular reminder of the real-world impact of this work.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates a new PRDM5 gene variant linked to brittle cornea syndrome (BCS) in three siblings from a Laotian family, detailing their ophthalmic symptoms like myopia and thin corneas.
- All three children were found to be homozygous for the PRDM5 variant, and the youngest underwent a corneal transplant due to severe issues, with histopathology showing significant corneal damage.
- Findings suggest that the novel PRDM5 variant likely causes the observed BCS symptoms, with the surgical challenges also highlighted due to the fragility of the affected tissues.
Article Synopsis
- Alkali injuries to the eyes are urgent situations that can lead to serious, long-lasting damage to vision if not treated immediately.
- Treatment typically focuses on neutralizing the chemical damage, managing inflammation, and helping the eye heal effectively.
- A case study of a 35-year-old man exposed to sodium hydroxide illustrates successful recovery using an amniotic membrane and a special ring, resulting in improved vision four months later.