Publications by authors named "B F Othman"
The intersubject reliability of cortical auditory evoked potential (CAEP) in pediatric cochlear implant recipients: comparisons between acoustic and electrical stimulations.
Rosninda Abdullah Nashrah Maamor Mohd Normani Zakaria Nik Adilah Nik Othman Basyariatul Fathi Othman
Eur Arch Otorhinolaryngol
November 2024
Article Synopsis
- The study aims to compare the reliability of cortical auditory evoked potentials (CAEP) generated by acoustic versus electrical stimuli in children with cochlear implants.
- Involving 22 pediatric cochlear implant recipients, the research found that acoustic stimuli resulted in more reliable latency measurements compared to electrical stimuli, with significant differences noted in both latency and amplitude metrics.
- The findings suggest that acoustic CAEP testing is more consistent than electrical CAEP testing, providing valuable insights for researchers and clinicians working with cochlear implant recipients.
Sclerosing mucoepidermoid carcinoma (SMEC) of the salivary glands is a rare variant of low-grade mucoepidermoid carcinoma with scanty cellular atypia characterized by marked fibrosis/sclerosis and a rich inflammatory infiltrate. Herein, we report 25 unpublished cases of SMEC, two of them with prominent eosinophilia (2/25; 8%) and three with abundant IgG4-positive plasma cells (3/25; 12%). In our series of salivary SMEC, molecular analysis using fluorescence in situ hybridization (FISH) and/or next-generation sequencing (NGS) provided evidence of MAML2 gene rearrangement in 18 cases of the 21 analyzable cases tested (86%), while this gene locus was intact in 3 cases (14%).
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- Methicillin-Resistant Staphylococcus aureus (MRSA) is a highly resistant bacteria causing various infections, and phages are seen as a promising alternative to antibiotics for treatment.
- The study isolated a novel lytic phage, vB_SauP_ASUmrsa123, from sewage and clinical samples, confirming its effectiveness against MRSA using plaque assays and examining its morphology via electron microscopy.
- Genome sequencing revealed that the phage has a linear dsDNA of approximately 17,155 bp with 24 predicted open reading frames (ORFs), suggesting its potential for targeting MRSA in infections.
Article Synopsis
- A novel, eco-friendly method for producing copper nanoparticles (CuNPs) has been developed using Priestia sp. bacteria, utilizing low-cost agro-industrial wastes instead of traditional glucose and copper ions.
- Characterization techniques such as UV-visible spectroscopy and X-ray diffraction confirmed the formation and size of the CuNPs, with notable findings including a maximum concentration of 6.19 ppm and effective size reduction to 3.12 nm when using blackstrap sugar cane molasses.
- The biosynthesized CuNPs displayed significant antibacterial properties against Bacillus cereus and Staphylococcus aureus, along with antitumor effects, indicating potential applications in medical and environmental fields.
Article Synopsis
- - Leishmaniasis affects 98 countries, primarily causing severe illness and death, especially in its visceral form, necessitating the development of better treatments due to ineffective current options and side effects of existing drugs.
- - A study identified nine natural compounds that inhibit the APX enzyme in Leishmania donovani, with estradiol cypionate showing the strongest binding affinity, indicating potential for effective treatment.
- - The compounds exhibited favorable drug-like properties, suggesting they could lead to novel oral treatments for leishmaniasis and warrant further research into their therapeutic potential.