Publications by authors named "B F Hudson"

Background: Housing insecurity can be linked to bereavement and is often caused or exacerbated by loss of household income and restrictions to some tenancy agreements. Housing insecurity can result in significant practical disruption, increase risk of adverse health outcomes and decrease quality of life. However, despite the impact of housing insecurity on experiences following bereavement, little is known about its underlying risk factors.

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Background: All IN for Health is a well-established community-academic partnership dedicated to helping improve the lives of Indiana residents by increasing health research literacy and promoting health resources, as well as opportunities to participate in research. It is sponsored by the Indiana Clinical and Translational Science Institute (I-CTSI). The study's purpose was to measure trust in biomedical research and healthcare organizations among research volunteers.

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Article Synopsis
  • Constitutive activity of G protein-coupled receptors, like GPR35, plays a key role in maintaining the integrity of the epithelial barrier in the gut, which is crucial for preventing inflammatory diseases.
  • Studies showed that certain inverse agonists could disrupt this barrier function in colonic organoids, suggesting the importance of GPR35's ongoing, or "constitutive," activation.
  • The research found that the activity of GPR35 varies depending on the specific signaling pathways and levels of receptor expression, highlighting its complex role in cellular responses and potential therapeutic implications for inflammatory bowel conditions.
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The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, RCSB.org), the US Worldwide Protein Data Bank (wwPDB, wwPDB.org) data center for the global PDB archive, provides access to the PDB data via its RCSB.

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Article Synopsis
  • The study focused on the CAD-RADS system to standardize CTCA reporting and explored how coronary calcification affects the assessment of stenosis in patients.
  • Researchers hypothesized that the Fractional Flow Reserve (FFRCT) would be lower for calcified stenoses (Ca+) compared to non-calcified ones (Ca-) in the same CAD-RADS categories.
  • Results showed that there was no significant difference in FFRCT values between Ca+ and Ca- stenoses for most categories, but CAD-RADS 3 Ca+ had lower FFRCT readings, suggesting possible underestimation that was not confirmed with invasive tests.
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