Publications by authors named "B F Hanna"
Stereotactic systems have traditionally used Cartesian coordinate combined with linear algebraic mathematical models to navigate the brain. Previously, the development of a novel stereotactic system allowed for improved patient comfort, reduced size, and carried through a simplified interface for surgeons. The system was designed with a work envelope and trajectory range optimized for deep brain stimulation applications only.
View Article and Find Full Text PDFFunctional cell death pathways are essential for normal ocular vascular development and tissue homeostasis. As our understanding of necrosis-based cell death pathways has expanded, the inclusion of regulated forms, including necroptosis, ferroptosis, and oxytosis, has occurred. Although the existence of these pathways is well described, our understanding of their role during vascular development and pathological neovascularization is very limited.
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- A 70-year-old man with complete blindness in one eye experiences worsening vision in the other due to idiopathic pachymeningitis affecting the optic nerve.
- An MRI indicated optic neuropathy due to the condition, leading to the patient undergoing endoscopic optic nerve decompression surgery.
- Post-surgery, his visual acuity remained the same at 6 weeks but drastically worsened at one year, while his color vision showed no improvement, indicating the procedure did not achieve the desired outcome.
Article Synopsis
- - Patients with repaired tetralogy of Fallot are prone to ventricular tachycardia and sudden cardiac death, with most arrhythmias linked to specific slow-conducting areas in the heart known as SCAIs.
- - The study compared a "prophylactic" approach, which involved ablating SCAIs regardless of whether VT was induced, to a "historical" approach that used VT induction to guide treatment, focusing on reducing complications and the need for implantable cardioverter-defibrillators (ICDs).
- - Results showed that patients who underwent prophylactic ablation had no major arrhythmic events over a median follow-up of 21 months, whereas 29% of the historical group
In the aging population, choroidal vessels grow through the Bruch's membrane, resulting in a loss of central vision due to choroidal neovascularization (CNV). During active neovascularization, CNV is associated with inappropriate levels of apoptosis in multiple cell types, including choroidal endothelial cells (ChECs). Bim is a pro-apoptotic member of the Bcl-2 family.
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