Publications by authors named "B F Funk"
Artificial intelligence promises to revolutionize mental health care, but small dataset sizes and lack of robust methods raise concerns about result generalizability. To provide insights on minimal necessary data set sizes, we explore domain-specific learning curves for digital intervention dropout predictions based on 3654 users from a single study (ISRCTN13716228, 26/02/2016). Prediction performance is analyzed based on dataset size (N = 100-3654), feature groups (F = 2-129), and algorithm choice (from Naive Bayes to Neural Networks).
View Article and Find Full Text PDFArticle Synopsis
- - The study investigates the cost-effectiveness of a digital stress management intervention for employees versus a waitlist control group over six months, focusing on health costs and productivity losses.
- - Results indicate that the intervention is likely to be cost-effective from both societal and employer perspectives, with a high probability of being dominant and providing a positive return on investment.
- - Overall, the findings suggest that digital stress management programs not only improve employee wellbeing but also offer economic benefits, making them a worthwhile investment for employers.
Vitamin B (VB) is a flexible and sustainable catalyst both in nature and the reaction flask, facilitating varied organic transformations of high value to both enzymatic processes and synthetic chemists. Key to this value is the breadth of reactivity it possesses, capable of both ionic, 2 electron chemistry, and radical, 1 electron chemistry. In particular, the ability to generate carbon-centered radical intermediates via photolysis of organocobalt intermediates formed from alkyl electrophiles opens the door to powerful new radical transformations challenging to achieve using classical photoredox or ligand-to-metal charge transfer (LMCT) catalysis.
View Article and Find Full Text PDFArticle Synopsis
- Clozapine is the top antipsychotic for treatment-resistant psychosis, but its use is limited by concerns over agranulocytosis, a potentially dangerous side effect; however, recent evidence suggests not all low blood cell counts indicate this severe reaction.
- The study aimed to analyze the occurrence and timing of clozapine-induced agranulocytosis using various diagnostic criteria, focusing on demographic differences among patients in the UK Central Non-Rechallenge Database.
- Findings showed that 19.6% of patients had threshold-based agranulocytosis, with a higher prevalence in older age groups and among White and male individuals, suggesting a need to reconsider how clinicians assess clozapine's risks and benefits. *
Article Synopsis
- Research indicates that machine learning (ML) algorithms utilizing natural behavior data (like text, audio, and video) could enhance personalization in psychology and psychiatry, but there's a lack of a comprehensive review on this topic.
- The systematic review analyzed 128 studies, predominantly focusing on predicting anxiety (87 studies) and posttraumatic stress disorder (41 studies), mostly published since 2019 in computer science journals, with a greater emphasis on text data.
- While many studies showed promising predictive power, significant variations in quality and reporting standards exist, and further standardization and research in clinical settings are needed for effective application in mental health diagnostics.