Publications by authors named "B Erbay"
Article Synopsis
- - This study compares chronic immobilization stress (CIS) and cisplatin treatments as models for studying premature ovarian failure (POF) in rats, focusing on their effects on ovarian function and the potential benefits of a mitochondrial protective agent (AP39).
- - Sixty female rats were divided into six groups to assess different treatment combinations and evaluate factors like hormonal levels, estrous cycles, and ovarian health through various tests and observations.
- - The results showed that both CIS and cisplatin treatments led to significant declines in ovarian health markers, and AP39 did not fully return these parameters to normal, suggesting that the CIS model may better represent stress-induced ovarian dysfunction rather than typical POF.
Introduction: This study aimed to determine polypharmacy, potentially inappropriate medications, and potential drug-drug interactions in elderly patients hospitalized in the oncology services of a university hospital in Turkey.
Methods: This retrospective cross-sectional study was conducted between September 2021 and September 2022 on cancer patients over 65 years old hospitalized at Suleyman Demirel University Medical Faculty Hospital in Isparta, Turkey. Potentially inappropriate medications were defined according to the 2023 Beers Criteria of the American Geriatrics Society.
Nuclear bodies (NBs) are dynamic structures present in eukaryotic cell nuclei. They are not bounded by membranes and are often considered biomolecular condensates, defined structurally and functionally by the localisation of core components. Nuclear architecture can be reorganised during normal cellular processes such as the cell cycle as well as in response to cellular stress.
View Article and Find Full Text PDFThe architecture of sub-nuclear structures of eucaryotic cells is often changed during the infectious cycle of many animal and plant viruses. Cajal bodies (CBs) form a major sub-nuclear structure whose functions may include the regulation of cellular RNA metabolism. During the lifecycle of human adenovirus 5 (Ad5), CBs are reorganized from their spherical-like structure into smaller clusters termed microfoci.
View Article and Find Full Text PDFBackground: The aim of the study was to investigate the association of paraoxonase 1 (PON1) polymorphism, PON1/arylesterase (ARE) activity and oxidative stress index (OSI) in breast cancer (BC) patients with type 2 diabetes (DM).
Methods: Our study group consisted of 30 healthy women (HV group) and 66 female BC patients. The BC patients were divided into two groups: those with (n=37) and without DM (n=29) (BDM and NBDM group).