Automatic identification of ablation targets in persistent atrial fibrillation: Initial experience with a new mapping tool.

Introduction: Strategies beyond pulmonary vein isolation (PVI) in persistent atrial fibrillation (persAF) are debated. A novel mapping tool provides algorithmic detection of ablation targets based on electrogram (EGM) properties specific to stable localized rotational activations.

Methods: The mapping tool was used on 31 patients (20 de novo).

Single-Wire Control and Fault Detection for Automotive Exterior Lighting Systems.

The design of exterior lighting is crucial for automotive manufacturers to ensure the visibility and safety of the driver. This article proposes a new strategy to control and diagnose one or more exterior lighting functions in electric vehicles by maximising the electrical faults that are detected and their transfer over a single-wire. The outcome is a decreased system cost and an additional method for vehicle lighting infrastructure control and diagnosis.

Exploring Arylazo-3,5-Bis(trifluoromethyl)pyrazole Switches.

Arylazopyrazoles stand out among the azoheteroarene photoswitches due to their excellent properties in terms of stability of the least stable isomer and conversion between isomers, leading to their use in several interesting applications. We report herein the synthesis of arylazo-trifluoromethyl-substituted pyrazoles and their switching behavior under light irradiation. UV-vis and NMR experiments showed that arylazo-1-3,5-bis(trifluoromethyl)pyrazoles displayed very long half-lives in DMSO (days), along with reasonable values of other parameters that characterize a photoswitch.

Slow Conduction Corridors and Pivot Sites Characterize the Electrical Remodeling in Atrial Fibrillation.

Objectives: This study aimed to evaluate the progression of electrophysiological phenomena in a cohort of patients with paroxysmal atrial fibrillation (PAF) and persistent atrial fibrillation (PsAF).

Background: Electrical remodeling has been conjectured to determine atrial fibrillation (AF) progression.

Methods: High-density electroanatomic maps during sinus rhythm of 20 patients with AF (10 PAF, 10 PsAF) were compared with 5 healthy control subjects (subjects undergoing ablation of a left-sided accessory pathway).