Baroreflex Sensitivity and Long-Term Dementia Risk in Older Adults.

Background: Increased blood pressure (BP) variability is linked to dementia risk, but the relationship between baroreflex sensitivity (BRS), a fundamental mechanism for maintaining stable BP, and dementia risk is undetermined.

Methods: We tested the hypothesis that impaired BRS is associated with increased dementia risk in 1819 older adults (63% women; age, 71.0±6.

Associations Between Physical, Cognitive, and Mental Health Domains of Post-Intensive Care Syndrome and Quality of Life: A Longitudinal Multicenter Cohort Study.

Objectives: To explore associations between the physical, cognitive, and mental post-intensive care syndrome (PICS) health domains with changes in health-related quality of life (HRQoL) following ICU admission.

Design: A longitudinal prospective multicenter cohort study.

Setting/patients: Patients (n = 4092) from seven Dutch ICUs.

Discrepancy Between Functional Outcomes and Perceived Health post-ICU: A Prospective Cohort Study.

Rationale: Despite functional impairments, ICU survivors can perceive their quality of life as acceptable.

Objectives: To investigate discrepancies between calculated health, based on self-reported physical, mental and cognitive functioning, and perceived health one year after ICU admission.

Methods: Data from an ongoing prospective multicenter cohort study, MONITOR-IC, were used.

Improving patient care transitions from the intensive care unit to the ward by learning from everyday practice. A multicenter qualitative study.

Objective: To explore and describe the everyday practices (Work-As-Done) that hinder and facilitate patient care transitions from the intensive care unit (ICU) to the ward.

Research Method/design: Multiple qualitative case studies in the ICU and various specialized wards of three Dutch hospitals. Adult patients planned to be transferred were purposively sampled on a variety of characteristics along with their relative (if present), and the ICU and ward nurses who were involved in the transition process.

Reducing administrative burden by implementing a core set of quality indicators in the ICU: a multicentre longitudinal intervention study.

Background: The number of quality indicators for which clinicians need to record data is increasing. For many indicators, there are concerns about their efficacy. This study aimed to determine whether working with only a consensus-based core set of quality indicators in the intensive care unit (ICU) reduces the time spent on documenting performance data and administrative burden of ICU professionals, and if this is associated with more joy in work without impacting the quality of ICU care.