Publications by authors named "B E Sumpio"

Article Synopsis
  • * The evaluation highlighted areas where the AI struggled, particularly in interpreting complex medical scenarios and demonstrated issues with context understanding, leading to errors in 27% of cases.
  • * Although GPT-4 showed potential for clinical relevance, further scrutiny of its reasoning and accuracy is necessary before fully relying on it in a medical setting.
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Anterior lumbar interbody fusion (ALIF) is a standard approach for the surgical management of patients with severe degenerative disease at the L4-L5 and lumbosacral (L5-S1) levels. ALIF is performed through retroperitoneal exposure but harbors a small risk of major vascular injury. In this case, we describe an emergent endovascular repair of an external iliac vein injury that occurred during ALIF with long-term follow-up.

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Article Synopsis
  • The study analyzed serum samples from diabetic patients with diabetic foot ulcers (DFU) to identify proteins that could predict healing and serve as biomarkers for treatment.
  • Among the findings, certain interleukins (IL-10, IL-4, IL-5, IL-6, and IL-13) were elevated in patients who healed, while others (Fractalkine, IL-8, and TNFα) were higher in those who did not.
  • IL-10 emerged as the strongest predictor for healing, suggesting that measuring multiple serum proteins could enhance clinical management of DFU compared to using single biomarkers.
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Diabetes mellitus (DM) affects over 422 million people globally. Patients with DM are subject to a myriad of complications, of which diabetic foot ulcers (DFUs) are the most common with ∼25% chance of developing these wounds throughout their lifetime. Currently there are no therapeutic RNAs approved for use in DFUs.

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