Publications by authors named "B E Rose"
Background Setting: Punitive approaches to deter offending remain popular despite limited evidence of their effectiveness. This study investigated what effect presenting empirical criminological findings about the effectiveness of deterrence to a general public has on their punishment preferences. It builds on earlier research showing that such presentation reduces the public's inclination towards strict punishment.
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- The study assesses real-world outcomes and failure patterns in patients with muscle-invasive bladder cancer (MIBC) who underwent trimodality therapy (TMT) between 2000 and 2018, utilizing data from the Veterans Affairs database.
- Results indicate that out of 347 patients treated with TMT, 44% had no recurrence, while 37% experienced metastatic recurrence (MR) and 34% had local recurrence (LR), highlighting significant rates of recurrence within the patient population.
- The findings suggest that TMT is generally effective in treating MIBC, but the high recurrence rates, particularly with lymph node positive disease and pre-treatment hydronephrosis, stress the importance of ongoing patient monitoring and the exploration of better treatment strategies
Background: The mechanisms underlying postoperative atrial fibrillation (POAF) remain unclear.
Objectives: The aim of this study was to test the hypothesis that targeted chemical ganglionated plexi (GP) modulation of all major left atrial-pulmonary vein GP using novel nanoformulated calcium chloride (nCaCl) can reverse postoperative neuroelectrical remodeling by suppressing vagosympathetic nerve activity and the localized inflammatory process, both critical substrates of POAF.
Methods: In a novel canine model of POAF with serial thoracopericardiotomies, sympathetic nerve activity (SNA), vagal nerve activity (VNA) and GP nerve activity (GPNA) were recorded; spontaneous and in vivo AF vulnerability were assessed; and atrial and circulating inflammatory markers and norepinephrine (NE) were measured to determine the neuroelectrical remodeling that promotes POAF and its subsequent modulation with nCaCl GP treatment (n = 6) vs saline sham controls (n = 6).
Background: Māori (the Indigenous people of Aotearoa New Zealand) report higher rates of eating disorders than non-Māori, but access treatment at lower rates. Diagnostic terms lacking in cultural relevance likely contribute to Māori exclusion in eating disorder spaces. Developing terms in te reo Māori (the Māori language) presents an opportunity to challenge eating disorder stereotypes and increase cultural safety in the eating disorder workforce.
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