Background/objectives: This study aimed to address limitations of the pilot reliability study on the Sensory-Motor Dysfunction Questionnaire (SMD-Q) in two parts. Part 1 evaluated the intra-rater reliability of SMD-Q version 2 (V2). Part 2 addressed V2's limitations before assessing the intra-rater reliability of version 3 (V3).
View Article and Find Full Text PDFThyroid cancer progression from curable well-differentiated thyroid carcinoma to highly lethal anaplastic thyroid carcinoma is distinguished by tumor cell de-differentiation and recruitment of a robust stromal infiltrate. Combining an integrated thyroid cancer single-cell sequencing atlas with spatial transcriptomics and bulk RNA-sequencing, we define stromal cell subpopulations and tumor-stromal cross-talk occurring across the histologic and mutational spectrum of thyroid cancer. We identify distinct inflammatory and myofibroblastic cancer-associated fibroblast (iCAF and myCAF) populations and perivascular-like populations.
View Article and Find Full Text PDFCamera traps are widely used in wildlife research and monitoring, so it is imperative to understand their strengths, limitations, and potential for increasing impact. We investigated a decade of use of wildlife cameras (2012-2022) with a case study on Australian terrestrial vertebrates using a multifaceted approach. We (i) synthesised information from a literature review; (ii) conducted an online questionnaire of 132 professionals; (iii) hosted an in-person workshop of 28 leading experts representing academia, non-governmental organisations (NGOs), and government; and (iv) mapped camera trap usage based on all sources.
View Article and Find Full Text PDFThe evaluation of the shedding capacity of a garment is crucial in forensic analysis to understand fibre transfer mechanisms during contact activities. While adhesive tapes are commonly used, the lack of standardised pressure application -often done manually- poses a challenge. In addition, while previous studies have examined the effects of washing on fibre evidence, there is a notable absence in the literature regarding its impact on garment shedding capacity.
View Article and Find Full Text PDFPurpose: Proctectomy is frequently deferred at index colectomy for ulcerative colitis due to acuity or immunosuppressive treatments. The retained rectum remains symptomatic in over 50% with associated cancer risk. Management options include index or delayed proctectomy with or without restoration of continuity or surveillance.
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