The production of biopharmaceuticals is a chemical- and water-intensive process. The consumption of water and chemicals is partly due to the need for many different buffers in large volumes during the downstream process, typically consisting of several chromatography steps. Given the global commitment to the goals for sustainable development and the anticipated growth of the biopharmaceutical market, the consumption of large buffer volumes is expected to become problematic.
View Article and Find Full Text PDFIn recent years, a relatively large number of articles in the Swedish media have reported on the problems that afflict nursing homes due to prolonged and climate-related heatwaves during the summer months. Older residents are badly affected by the heat, especially as many nursing homes in Sweden lack air conditioning. This paper aims to explore how nursing homes are depicted in the Swedish press in relation to climate-related heatwaves, professional care, and risk management.
View Article and Find Full Text PDFObjectives: The purpose of this study was to describe the experiences and actions of part-time firefighters' family members in rural areas in Sweden.
Design: The study had an inductive descriptive design and used the critical incident technique.
Setting: Rural areas, primarily served by a part-time fire station, across Sweden.
Mosaic chromosomal alterations (mCAs) in hematopoietic cells increase mortality and risk of hematological cancers and infections. We investigated the landscape of mCAs and their clinical consequences in 976 patients with multiple myeloma undergoing high-dose chemotherapy and autologous stem cell support (ASCT) with median 6.4 years of follow-up.
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