Publications by authors named "B E A Fantinatti"
Background: B chromosomes (Bs) are extra elements observed in diverse eukaryotes, including animals, plants and fungi. Although Bs were first identified a century ago and have been studied in hundreds of species, their biology is still enigmatic. Recent advances in omics and big data technologies are revolutionizing the B biology field.
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- Colossoma macropomum (tambaqui) and Piaractus mesopotamicus (pacu) are valuable fish species for aquaculture, particularly the hybrid tambacu, which shows significant growth and strength, making it popular in Brazil.
- Small RNA sequencing was utilized to analyze miRNA expression across three fish genotypes: pacu, tambaqui, and hybrid tambacu, aiming to understand the muscle growth mechanisms in the hybrid.
- The study identified several differentially expressed miRNAs specific to genotype comparisons, with particular miRNAs linked to pathways involving oxygen regulation and muscle metabolism, highlighting their potential for enhancing fish farming efficiency.
Environmental exposure to phthalates during intrauterine development might increase susceptibility to neoplasms in reproductive organs such as the prostate. Although studies have suggested an increase in prostatic lesions in adult animals submitted to perinatal exposure to phthalates, the molecular pathways underlying these alterations remain unclear. Genome-wide levels of mRNAs and miRNAs were monitored with RNA-seq to determine if perinatal exposure to a phthalate mixture in pregnant rats is capable of modifying gene expression during prostate development of the filial generation.
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- Supernumerary B chromosomes are extra genetic elements found in some eukaryotes, including cichlid fish, and their role in these organisms is not fully understood.
- These B chromosomes are linked to changes in RNA transcription and affect epigenetic modifications such as 5-methylcytosine and 5-hydroxymethylcytosine levels in different tissues of males and females.
- The study suggests that the presence of B chromosomes can lead to changes in DNA epigenetic marks, impacting cell function and possibly explaining how sex influences B chromosome effects.
B chromosomes are dispensable elements observed in many eukaryotic species, including the African cichlid Astatotilapia latifasciata, which might have one or two B chromosomes. Although there have been many studies focused on the biology of these chromosomes, questions about the evolution, maintenance, and potential effects of these chromosomes remain. Here, we identified a variant form of the hnRNP Q-like gene inserted into the B chromosome of A.
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