[Primary disability as a consequence of tuberculosis and the factors that contribute to its development].

Analysis is given of a high level of invalidity in 508 patients in four regions to whom invalidity due to tuberculosis was first established in 1987-1989. The main factors responsible for invalidity included progress of a tuberculous process, ineffective chemotherapy, untimely diagnosis, the presence of serious attendant diseases, functional disorders of the affected organs, complication of the disease, asocial way of life (chronic alcoholism, narcomania), and insufficient material provision of large families. Most invalids had a combination of the above factors.

[Experimental and clinical study test of capreomycin].

Data on the experimental and clinical study of capreomycin in the treatment of tuberculosis are presented. It was shown that capreomycin had low activity with respect to the sensitive strain of Mycobacterium tuberculosis H37 Rv in vitro and the respective infection caused by it in mice. The activity of capreomycin in vitro with respect to streptomycin resistant strains was the same as that with respect to the sensitive strains, while in vivo it increased 3 times.