Publications by authors named "B Drugeon"

Article Synopsis
  • Early identification of patients at high risk for PIVC-related phlebitis is crucial to prevent complications associated with medical devices.
  • The study developed and validated four machine learning models to predict phlebitis incidence in critically ill patients, using a large dataset of 3429 PIVCs.
  • Results showed that the Random Survival Forest (RSF) model had the best performance for predicting phlebitis, while key predictive factors included insertion site, catheter material, age, and medication use.
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Introduction: Peripheral intravenous catheters (PIVCs) are the most commonly used vascular access device in hospitalised patients. Yet PIVCs may be complicated by local or systemic infections leading to increased healthcare costs. Chlorhexidine gluconate (CHG)-impregnated dressings may help reduce PIVC-related infectious complications but have not yet been evaluated.

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Aim: Although uncommon, infections associated with peripheral intravenous catheters (PIVCs) may be responsible for severe life-threatening complications and increase healthcare costs. Few data are available on the relationship between PIVC insertion site and risk of infectious complications.

Methods: We performed a post hoc analysis of the CLEAN 3 database, a randomized 2 × 2 factorial study comparing two skin disinfection procedures (2% chlorhexidine-alcohol or 5% povidone iodine-alcohol) and two types of medical devices (innovative or standard) in 989 adults patients requiring PIVC insertion before admission to a medical ward.

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Background: Anaemia and blood transfusion are associated with poor outcomes after hip fracture. We evaluated the efficacy of intravenous iron and tranexamic acid in reducing blood transfusions after hip fracture surgery.

Methods: In this double-blind, randomised, 2 × 2 factorial trial, we recruited adults hospitalised for hip fractures in 12 medical centres in France who had preoperative haemoglobin concentrations between 9·5 and 13·0 g/dL.

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Background: Peripheral venous catheter (PVC) complications occur on average in approximately half of patients, necessitating premature PVC removal, suspending administration of ongoing therapies, and catheter replacement.

Aim: To estimate the current incidence, complications, and costs of bloodstream infection (BSI) attributable to PVCs.

Methods: Patients with PVC-related BSI (cases) were matched with patients without PVC-related BSI (controls).

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