Publications by authors named "B Dell'Osso"

Introduction/objective: Data on long-term treatment with Esketamine Nasal Spray (ESKNS) in real-world patients with treatment resistant depression (TRD) is scarce. The primary aim of the study is to evaluate the effectiveness and tolerability of ESK-NS treatment at 6 and 12-month follow-ups.

Methods: This is part of an observational, retrospective, multicentric Italian study (REAL-ESK study).

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: The COVID-19 pandemic had a negative impact on mental health in the general population. The fear, stress, and uncertainty surrounding that traumatic period could have contributed to the aggravation or possible new onset of obsessive-compulsive symptoms. The COvid Mental hEalth Trial (COMET) is a nationwide project organized by the University of Campania "Luigi Vanvitelli", designed as an observational investigation that aimed to gather data from a representative sample of the Italian general population.

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Objective: Cognitive and psychiatric symptoms have been increasingly reported after severe acute respiratory syndrome coronavirus 2 infection, developing soon after infection and possibly persisting for several months. We aimed to study this syndrome and start implementing strategies for its assessment.

Methods: Consecutive patients, referred by the infectious disease specialist because of cognitive complaints after COVID-19, were neurologically evaluated.

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Article Synopsis
  • * Out of 57 patients referred for psychiatric evaluation, nearly half were diagnosed with various disorders, including adjustment issues and anxiety, highlighting a significant link between cognitive complaints and mental health aftermath of COVID-19.
  • * The findings suggest that implementing psychiatric screenings for those with post-COVID cognitive symptoms can help in early diagnosis and treatment, potentially improving patient outcomes.
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Article Synopsis
  • * An online survey of 1,041 HWs revealed high levels of anxiety (58.1%), depression (27.5%), and trauma-related symptoms (25.9%), along with substantial functional impairment in 67.4% of the participants.
  • * The study suggests that prior mental health issues and being a parent to young children exacerbated the negative impacts on functioning, emphasizing the need for tailored support interventions for HWs during crises.
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