Publications by authors named "B De Vos"
Objective: Ensuring adequate bone health is crucial for preventing conditions such as osteoporosis and fractures. Zingerone, a phytonutrient isolated from cooked ginger, has gained attention for its potential benefits in bone health. This study evaluated the osteoprotective potential of zingerone and its effects on differentiation and signalling pathways using SAOS-2 osteosarcoma and RAW264.
View Article and Find Full Text PDFDisruptions of the eukaryotic plasma membrane due to chemical and mechanical challenges are frequent and detrimental and thus need to be repaired to maintain proper cell function and avoid cell death. However, the cellular mechanisms involved in wound resealing and restoration of homeostasis are diverse and contended. Here, it is shown that clathrin-mediated endocytosis is induced at later stages of plasma membrane wound repair following the actual resealing of the wound.
View Article and Find Full Text PDFAutomated echocardiography view classification and quality assessment with recognition of unknown views.
J Med Imaging (Bellingham)
September 2024
Article Synopsis
- The study aims to automate the selection process for echocardiographic exams by classifying routine views, recognizing unknown views, and assessing image quality.
- A neural network is trained for view classification, and a linear regression model predicts view quality using feature embeddings.
- Results show that the method performs nearly at expert level, significantly improving efficiency in selecting appropriate echocardiography views for analysis.
Low muscle quality on a procedural computed tomography scan assessed with deep learning as a practical useful predictor of mortality in patients with severe aortic valve stenosis.
Clin Nutr ESPEN
October 2024
Article Synopsis
- Accurate diagnosis of sarcopenia involves assessing muscle quality, specifically how much fat is infiltrated in muscle tissue, which is crucial for predicting mortality in TAVI patients.
- The study analyzed CT scans from 1199 patients who underwent TAVI between 2010 and 2020, employing deep learning algorithms to measure skeletal muscle density (SMD) and intermuscular adipose tissue (IMAT).
- Results indicated that low muscle quality, identified through both low SMD and high IMAT, significantly correlates with increased mortality risk, suggesting that muscle quality metrics are valuable predictors of health outcomes post-TAVI.
Characterizing intracellular mechanics via optical tweezers-based microrheology.
Curr Opin Cell Biol
June 2024
Intracellular organization is a highly regulated homeostatic state maintained to ensure eukaryotic cells' correct and efficient functioning. Thanks to decades of research, vast knowledge of the proteins involved in intracellular transport and organization has been acquired. However, how these influence and potentially regulate the intracellular mechanical properties of the cell is largely unknown.
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