Publications by authors named "B Dakshayani"

Background: Antibiotics play a critical role in neonatal sepsis but excessive use is associated with adverse outcomes and the current prescribing rates of antibiotics are unacceptably high.

Aim: To reduce antibiotic over-use in preterm neonates by implementing an antibiotic stewardship programme using a quality improvement (QI) initiative.

Methods: This study was conducted at a neonatal intensive care unit in a resource-limited setting.

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Scrub typhus has re-emerged as an important cause of acute febrile illness in India. There is a dearth of information on strain diversity of Orientia tsutsugamushi from Karnataka, India, hence the present study sought to address this issue. One hundred clinically suspected cases of scrub typhus/rickettsiosis (as per the DHR-ICMR guidelines) were included.

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Purpose: Newborn screening is the need of the hour in a developing country like India as there is paucity of data from studies conducted in government hospitals with large sample size. The purpose of the study is to estimate incidence rate and recall rates for five conditions screened in the neonatal period namely congenital hypothyroidism, congenital adrenal hyperplasia, glucose-6-phosphate dehydrogenase (G6PD) deficiency, galactosemia and phenyl ketonuria (PKU).

Methods: The study was conducted at VaniVilas Hospital attached to Bangalore Medical College and Research Institute.

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Article Synopsis
  • - The study aimed to identify factors that predict frequent relapses and steroid dependency in children with steroid-sensitive nephrotic syndrome, analyzing data from patients aged six months to 18 years from 2003 to 2015.
  • - Results showed that frequent relapsers were younger at onset and experienced their first relapse sooner than infrequent relapsers, with specific predictors like a first relapse occurring within six months and concomitant infection during relapses.
  • - The findings suggest that understanding these predictors can help improve patient management, targeting closer follow-ups and tailored treatment strategies.
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Article Synopsis
  • This study compared the effects of isotonic fluids (0.9% saline in 5% dextrose) and hypotonic fluids (0.18% saline in 5% dextrose) on hyponatremia in children in a pediatric intensive care unit (PICU).
  • Among 240 children, 16.7% in the hypotonic fluid group developed hyponatremia, while only 7.5% in the isotonic group did, indicating a significant difference (p = 0.029).
  • The findings suggest that isotonic fluids may reduce the risk of hyponatremia and shorten PICU stay for children, supporting their use as
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