Publications by authors named "B DE LA Salle"

Article Synopsis
  • Metabolomics is a new approach to identify biomarkers related to egg and embryo quality, which can help in understanding infertility issues.
  • Recent findings show that differences in metabolite concentrations in follicular fluid correlate with various infertility conditions, like endometriosis and polycystic ovary syndrome.
  • Larger studies and an international database are needed to validate these findings and potentially improve reproductive treatment outcomes by using biomarkers from follicular fluid.
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Introduction: This paper is a report of an ICSH review of policies and practices for internal quality control (IQC) policy for haematology cell counters among regulatory bodies, cell counter manufacturers and diagnostic laboratories. It includes a discussion of the study findings and links to separate ICSH guidance for such policies and practices. The application of internal quality control (IQC) methods is an essential pre-requisite for all clinical laboratory testing including the blood count (Full Blood Count, FBC, or Complete Blood Count, CBC).

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This paper is a description of the ICSH guidance for internal quality control (IQC) policy for blood cell counters. It follows from and links to a separate ICSH review for such policies and practices. The ICSH has gathered information regarding the current state of practice through review of published guidance from regulatory bodies, a questionnaire to six major cell counter manufacturers and a survey issued to 191 diagnostic laboratories in four countries (China, the Republic of Ireland, Spain, and the United Kingdom) on their IQC practice and approach to the use of commercial IQC materials.

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Background: Ejaculated spermatozoa are considered to possess a higher fertilisation potential than testicular spermatozoa. In selected cases, the use of testicular spermatozoa from non-azoospermic infertile men resulted in a higher implantation and pregnancy rate than the use of ejaculated spermatozoa.

Objective: The primary objective was to compare the live birth rate and cumulative live birth rate between couples with failed intracytoplasmic sperm injection procedure using ejaculated spermatozoa who subsequently had an intracytoplasmic sperm injection cycle with testicular spermatozoa and those who subsequently had an intracytoplasmic sperm injection cycle with ejaculated spermatozoa.

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Article Synopsis
  • The French National College of Obstetricians and Gynecologists updated their guidelines in 2018 to manage endometriosis pain, now incorporating new therapies and research up to 2021.
  • A new diagnostic approach using patient questionnaires and saliva analysis may help identify pelvic pain issues without the need for surgery.
  • Dienogest (DNG) is recognized as an effective first-line treatment for endometriosis pain, and new oral GnRH antagonists are expected to hit the French market soon, offering rapid results with easier administration compared to existing treatments.
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