Publications by authors named "B D Vaishnavi"
Article Synopsis
- Recent studies indicate that base editing can cause significant deletions in specific gene regions, which may reduce its therapeutic effectiveness even when fewer deletions occur compared to traditional Cas9 methods.
- The research explores using a dCas9 fusion of ABE8e instead of nickaseCas9 to maintain editing efficiency while minimizing these deletions in human hematopoietic stem and progenitor cells (HSPCs).
- Findings reveal that dABE8e allows for effective editing without creating large deletions, leading to a safer method for genome editing with improved precision.
Background: Despite many measures taken by the government, still the problem of Vitamin A deficiency and anaemia exists among children. This study focuses on coverage of iron and folic acid and Vitamin A supplementation among children aged between 9 months and 5 years and to find out the barriers in administrating these supplements to children.
Methods: An explanatory sequential mixed methodology was conducted in the field practice area of Thirubuvanai primary health centre.
Ebstein in Pregnancy: Can Combined Spinal-Epidural Anaesthesia be a Choice?
J Obstet Gynaecol India
February 2024
Surgical Efficacy of Mastoidectomy in Chronic Otitis Media: Squamosal Type.
Indian J Otolaryngol Head Neck Surg
April 2023
Chronic Otitis Media-Squamosal type is an erosive process, which when confined to ossicular chain causes varying degrees of hearing impairment. As the disease progresses to involve surrounding vital structures, it causes various complications like facial palsy, vertigo, mastoid abscess, which are more common than the other intracranial complications, and require a definitive surgical intervention i.e.
View Article and Find Full Text PDF