Publications by authors named "B D Minsky"

Article Synopsis
  • Current radiation oncology (RO) trainees lack formal mentorship and training on clinical trial design and implementation, relying mostly on informal education within residency programs.
  • The "Fletcher-Cox Pathway," initiated at MD Anderson Cancer Center in 2018, has successfully established a structured clinical trial training program for RO residents, receiving positive feedback and participation.
  • The program enables trainees to design and submit clinical trials, fostering mentorship relationships and aiming to create a national platform to enhance access to clinical trial education and resources in RO.
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We hypothesized that pre-consult patient education videos can improve patient understanding about their diagnosis, lead to high satisfaction and low distress. In this pilot study, we developed a patient education video curriculum for patients with newly-diagnosed anal cancer. Comprehension of key content was evaluated by comparing pre- and post-test scores.

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Article Synopsis
  • The study investigates the effectiveness of radiation therapy (RT) for intrahepatic cholangiocarcinoma (iCCA) and explores a new approach to assess treatment response using quantitative measures rather than traditional size-based methods.
  • By analyzing CT scans from 154 patients, researchers found that changes in viable tumor volume after RT are better indicators of overall survival (OS) compared to standard RECIST criteria, with a notable threshold of a 33% reduction in viable volume signaling optimal treatment response.
  • The findings highlight the potential for personalized RT approaches based on individual tumor characteristics, suggesting that mathematical models derived from CT imaging can improve patient outcomes by identifying optimal treatment protocols.
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Purpose: The purpose of this phase 1 trial was to evaluate the safety and toxicity of preoperative short-course chemoradiotherapy (CRT) as part of total neoadjuvant therapy (TNT) for patients with potentially resectable gastric or gastroesophageal adenocarcinoma.

Methods And Materials: Patients were enrolled between March 2021 and December 2022 and received CRT (30 Gy radiation in 10 fractions with concurrent capecitabine or 5-fluorouracil), then received systemic therapy for 2 months, and then underwent surgery. The primary endpoint was CRT safety; secondary endpoints were pathologic complete response, perioperative complications, and overall survival (OS).

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