Publications by authors named "B D Latham"
Background: Tetrachloroethylene (PCE) is a known neurotoxicant mainly observed in populations with high level occupational exposure. Health effects of low-level community exposure are poorly understood. This study evaluated PCE exposure and neurobehavioral performance in 6 to 11-year-old children living in a community with multiple PCE contamination sites.
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- Many animals have a second frequency filter for sound beyond just the eardrum, which is particularly interesting in the hearing mechanism of field crickets.
- Researchers found that a "dividing membrane" linked to the tracheal branches plays a key role in filtering and transmitting sound, and it resembles the eardrum in thickness.
- Advanced techniques like micro-computed tomography and laser vibrometry demonstrated that the sound vibrations detected by the eardrum are actually influenced by the coupling of this membrane, shedding light on the cricket's hearing and its potential applications in technology.
Informed consent is the process of obtaining permission from human participants to use their cells and tissues or otherwise include them in research studies. With informed consent, scientists can use human cells or tissues in experiments to learn more about the human body and to test new medicines. This article describes how these tissues are obtained, and the ethical concerns regarding the use of human tissues in research.
View Article and Find Full Text PDFSmall molecule kinase inhibitors are one of the fastest growing classes of drugs, which are approved by the US Food and Drug Administration (FDA) for cancer and noncancer indications. As of September 2023, there were over 70 FDA-approved small molecule kinase inhibitors on the market, 42 of which were approved in the past five years (2018-2023). This minireview discusses recent advances in our understanding of the pharmacology, metabolism, and toxicity profiles of recently approved kinase inhibitors with a central focus on tyrosine kinase inhibitors (TKIs).
View Article and Find Full Text PDFWhen looking for novel, simple, and energy-efficient solutions to engineering problems, nature has proved to be an incredibly valuable source of inspiration. The development of acoustic sensors has been a prolific field for bioinspired solutions. With a diverse array of evolutionary approaches to the problem of hearing at small scales (some widely different to the traditional concept of 'ear'), insects in particular have served as a starting point for several designs.
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