Publications by authors named "B D Klugherz"
Pulmonary vein stenosis (PVS) is an insidious diagnosis associated with morbidity and mortality. Pharmacologic therapy may suffice initially, but advanced stages demand mechanical intervention. Pulmonary stent implantation (PSI) and pulmonary balloon angioplasty (PBA) are common strategies, both carrying restenosis risks.
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- Despite advancements in coronary artery disease (CAD) management, major cardiovascular events continue, and the use of low-dose rivaroxaban (2.5 mg) in combination with aspirin is being analyzed for its effectiveness compared to aspirin alone.
- A meta-analysis of five randomized controlled trials with over 41,000 participants showed that low-dose rivaroxaban significantly lowers risks of all-cause mortality, myocardial infarction, and stroke, but increases the risk of major bleeding.
- The study concludes that while low-dose rivaroxaban offers survival benefits for CAD patients, careful consideration of bleeding risks is important, and further research is needed to evaluate its safety compared to other treatments like dual antiplatelet therapy
Background: Acute pulmonary embolism (PE) is a serious condition that needs quick and effective treatment. Anticoagulation therapy is the usual care for most PE patients but may not work well for higher-risk ones. Thrombolysis breaks the clot and improves blood flow.
View Article and Find Full Text PDFBackground: While it is understood that coronavirus disease 2019 (COVID-19) is primarily complicated by respiratory failure, more data are emerging on the cardiovascular complications of this disease. A subset of COVID-19 patients present with ST-elevations on electrocardiogram (ECG) yet normal coronary angiography, a presentation that can fit criteria for myocardial infarction with no obstructive coronary atherosclerosis (MINOCA). There is little known about non-coronary myocardial injury observed in patients with COVID-19, and we present a case that should encourage further conversation and study of this clinical challenge.
View Article and Find Full Text PDFSpontaneous Coronary Artery Dissection: A Case Series of 9 Patients With Literature Review.
J Investig Med High Impact Case Rep
April 2018
Spontaneous coronary artery dissection is an increasingly recognized nonatherosclerotic cause of acute coronary syndrome. Reports regarding the prognosis and natural history of this disease are limited. In addition to the diagnostic difficulty, this condition poses a significant therapeutic challenge due to the lack of specific management guidelines.
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