Publications by authors named "B D Kessing"
Article Synopsis
- A study was conducted to explore how STW5 (Iberogast) might alleviate heartburn in patients with functional dyspepsia and reflux symptoms, focusing on its effect on esophageal sensitivity and motility.
- In a double-blind, placebo-controlled trial with 18 patients, STW5 showed no significant difference overall in reflux symptom scores compared to placebo, but it did reduce certain specific scores related to gastroesophageal reflux disease.
- The treatment also demonstrated a reduction in acidic reflux events in patients with gastroesophageal reflux disease and increased time before acid perception in those with reflux esophagitis, suggesting STW5 may help reduce esophageal hypersensitivity.
Introduction: Although inability to belch has previously been linked to dysfunction of the upper esophageal sphincter (UES), its underlying pathogenesis remains unclear. Our aim was to study mechanisms underlying inability to belch and the effect of UES botulinum toxin (botox) injections in these patients.
Methods: We prospectively enrolled consecutive patients with symptoms of inability to belch.
Following publication of the original article [1], an error was reported in the tagging of Joël Fokom Domgue in the author group. The tagging in this correction article has been fixed.
View Article and Find Full Text PDFThe gene encoding the GTPase KRAS is frequently mutated in pancreatic, lung, and colorectal cancers. The KRAS fraction in the plasma membrane (PM) correlates with activation of the mitogen-activated protein kinase (MAPK) pathway and subsequent cellular proliferation. Understanding KRAS's interaction with the PM is challenging given the complexity of the cellular environment.
View Article and Find Full Text PDFBackground: A low cost and accurate method for detecting high-risk (HR) human papillomavirus (HPV) is important to permit HPV testing for cervical cancer prevention. We used a commercially available HPV method (H13, Hybribio) which was documented to function accurately in a reduced volume of cervical specimen to determine the most prevalent HPV types and the distribution of HPV infections in over 1795 cancer-free women in Guatemala undergoing primary screening for cervical cancer by cytology.
Methods: HR-HPV detection was attempted in cervical samples from 1795 cancer-free women receiving Pap smears using the Hybribio™ real-time PCR assay of 13 HR types.