Publications by authors named "B D Gregory"
While all native tRNAs undergo extensive post-transcriptional modifications as a mechanism to regulate gene expression, mapping these modifications remains challenging. The critical barrier is the difficulty of readthrough of modifications by reverse transcriptases (RTs). Here we use Induro-a new group-II intron-encoded RT-to map and quantify genome-wide tRNA modifications in Induro-tRNAseq.
View Article and Find Full Text PDFSoil-transmitted parasitic nematodes infect over 1 billion people worldwide and are a common source of neglected disease. Strongyloides stercoralis is a potentially fatal skin-penetrating human parasite that is endemic to tropical and subtropical regions around the world. The complex life cycle of Strongyloides species is unique among human-parasitic nematodes in that it includes a single free-living generation featuring soil-dwelling, bacterivorous adults whose progeny all develop into infective larvae.
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- Strong coupling between polarization and strain in ferroelectric complex oxides allows for significant tuning of their properties, particularly demonstrated in KNbO thin films.
- Applying biaxial strain can drastically increase the Curie temperature, with predictions indicating it could exceed 1325 K under certain conditions.
- Enhanced properties such as a 46% increase in remanent polarization and a 200% boost in optical second harmonic generation coefficients make lead-free KNbO a promising candidate for high-temperature ferroelectric memory and quantum computing applications.
Among many mRNA modifications, adenine methylation at the N position (N-methyladenosine, mA) is known to affect mRNA biology extensively. The influence of mA has yet to be assessed under drought, one of the most impactful abiotic stresses. We show that Arabidopsis thaliana (L.
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- * A multicomponent intervention included outreach methods like mailed tests, texts, and emails, along with enabling nurses to order screening tests directly.
- * Results showed a significant increase in CRC screening rates post-intervention, suggesting that similar strategies could effectively boost screening participation for this age group.