Publications by authors named "B D Gartrell"

Determination of acid-base status contributes important information about patient health, including for patients under anesthesia. There is a paucity of information about the determinants of acid-base status of large felids managed under anesthesia, and advancement of such knowledge may contribute to patient safety. This study serially monitored the individual metabolic acid-base status of 11 large felids, including lions (), tigers (), and cheetahs (), under general anesthesia.

View Article and Find Full Text PDF
Article Synopsis
  • - The SPOTLIGHT study aimed to improve representation of African American (AA) patients in prostate cancer clinical trials, finding that 17% of enrolled patients were AA, which is above the typical rate of 8.5% in oncology trials.
  • - Using a novel diagnostic tool, F-flotufolastat, the study evaluated its effectiveness in detecting prostate cancer in AA patients, recording a 93% detection rate which varied with prostate-specific antigen levels.
  • - Although the overall detection rate for AA patients was slightly higher in those with intact prostates, both AA and non-AA patients had similar performance after prostate surgery, with verified detection rates at 64% and positive predictive values at 68% for AA patients
View Article and Find Full Text PDF

Case History: In 2023, the New Zealand Department of Conservation seized 63 endemic reptiles that were being held without a permit. This group included three adult female West Coast green geckos ( that had been illegally removed from the wild 2 years earlier. They had been held in an outdoor enclosure with a pair of goldstripe geckos ().

View Article and Find Full Text PDF
Article Synopsis
  • Metastases, which are the spread of cancer cells to different organs, play a crucial role in the severity of renal cell carcinoma (RCC), with common sites being the lungs, bones, liver, and lymph nodes.
  • This study analyzed 657 tumor samples from both primary renal tumors and various metastatic sites to identify genomic and transcriptomic differences.
  • The findings reveal significant variations in tumor characteristics and the tumor microenvironment across different metastatic locations, highlighting the importance of these factors in creating targeted cancer treatments.
View Article and Find Full Text PDF

Context: Treatment decision-making (TDM) for patients with localized (LPC) or locally advanced (LAPC) prostate cancer is complex, and post-treatment decision regret (DR) is common. The factors driving TDM or predicting DR remain understudied.

Objective: Two systematic literature reviews were conducted to explore the factors associated with TDM and DR.

View Article and Find Full Text PDF