The effects of handling on stress response markers in a reef fish model for aquaculture development, the brassy chub, Kyphosus vaigiensis.

With the expanding global population, interest has increased in the sustainable aquaculture development of indigenous fishes. In Hawai'i, the brassy chub, Kyphosus vaigiensis, has drawn interest as a candidate species for production. However, little is known about its resilience in aquaculture settings where fish are exposed to acute, husbandry-related stressors.

Recurrent Gastrointestinal Symptoms and Diagnosis of Superior Mesenteric Artery Syndrome.

This is a case of a young lady who was admitted multiple times with complaints of inability to digest food and abdominal pain. She had nausea and vomiting for long periods and was unable to tolerate orally. As she was unable to tolerate oral feeding and losing weight, she was started on nasogastric feed (NG feed) and later percutaneous endoscopic gastrostomy (PEG) tube feeding because NG feed was uncomfortable for the patient and did not alleviate the problem.

IL-12 drives the expression of the inhibitory receptor NKG2A on human tumor-reactive CD8 T cells.

Blockade of NKG2A/HLA-E interaction is a promising strategy to unleash the anti-tumor response. Yet the role of NKG2A CD8 T cells in the anti-tumor response and the regulation of NKG2A expression on human tumor-infiltrating T cells are still poorly understood. Here, by performing CITE-seq on T cells derived from head and neck squamous cell carcinoma and colorectal cancer, we show that NKG2A expression is induced on CD8 T cells differentiating into cytotoxic, CD39CD103 double positive (DP) cells, a phenotype associated with tumor-reactive T cells.

Promoting Physical Activity Among Health Professional Students, Faculty, and Staff Members: A Competition-Based Intervention.

This program review presents data for the Deans' Fit Family Challenge (DFFC) and proposes future directions for improvement, informed by the Social Cognitive Theory. The DFFC is a multi-week physical activity competition held annually between three health professional programs, focusing on the development of self-efficacy, self-regulation, and social support of health-related fitness. Participants competed in teams of two and tracked their activity minutes weekly using the ChallengeRunner app or through manual entry.