Publications by authors named "B D'ALESSANDRO"

AI image classification algorithms have shown promising results when applied to skin cancer detection. Most public skin cancer image datasets are comprised of dermoscopic photos and are limited by selection bias, lack of standardization, and lend themselves to development of algorithms that can only be used by skilled clinicians. The SLICE-3D ("Skin Lesion Image Crops Extracted from 3D TBP") dataset described here addresses those concerns and contains images of over 400,000 distinct skin lesions from seven dermatologic centers from around the world.

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Article Synopsis
  • Late alopecia, which is incomplete hair regrowth after chemotherapy or endocrine therapy, affects women's quality of life, leading this study to investigate oral minoxidil as a treatment option.
  • The study included 216 patients, primarily women with breast cancer, and found that 74% experienced improvement in hair regrowth after using oral minoxidil for about 3.5 months.
  • Results showed significant increases in hair density on both the frontal and occipital areas, indicating that oral minoxidil is well-tolerated and may help cancer survivors with late alopecia.
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Introduction: Artificial Intelligence (AI) has proven effective in classifying skin cancers using dermoscopy images. In experimental settings, algorithms have outperformed expert dermatologists in classifying melanoma and keratinocyte cancers. However, clinical application is limited when algorithms are presented with 'untrained' or out-of-distribution lesion categories, often misclassifying benign lesions as malignant, or misclassifying malignant lesions as benign.

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Background: The use of tissue fillers to treat age-related deepening of the nasolabial fold (NLF) has increased and become the standard clinical approach, creating a need for evidence-based, objective evaluation for pre- and post-procedure assessment of the NLF.

Methods: A 5-point rating scale was developed to assess the NLF, specifically the presence of depression and shadowing. Live validation of the scale was performed with a total of 73 participants representing the full range of NLF severities.

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