Publications by authors named "B Cuzin"
Objectives: The Association Interdisciplinaire Post-Universitaire de Sexologie (AIUS) has brought together a panel of experts to draw up French recommendations for the management of premature ejaculation. This article presents the recommendations for the diagnosis and evaluation of premature ejaculation.
Methods: Systematic review of the literature between 01/1995 and 02/2022.
Background: Steroidogenic factor 1 (SF-1), encoded by the nuclear receptor subfamily 5 group A member 1 () gene, is a transcriptional factor crucial for adrenal and gonadal organogenesis. Pathogenic variants of are responsible for a wide spectrum of phenotypes with autosomal dominant inheritance including disorders of sex development and oligospermia-azoospermia in 46,XY adults. Preservation of fertility remains challenging in these patients.
View Article and Find Full Text PDFObjectives: The Post-University Interdisciplinary Association of Sexology (AIUS) has brought together a panel of experts to develop French recommendations for the management of premature ejaculation.
Methods: Systematic review of the literature between 01/1995 and 02/2022. Use of the clinical practice guidelines (CPR) method.
Article Synopsis
- The study investigates whether testicular sperm extraction (TESE) should be done after puberty or delayed until adulthood in patients with non-mosaic 47,XXY Klinefelter syndrome (KS).
- Results show no significant difference in sperm retrieval rate (SRR) between younger patients (ages 15-22) and older patients (ages 23-43), with overall SRR at 45.4%.
- Key hormonal factors like Anti-Müllerian hormone (AMH) and inhibin B were found to be higher in the younger group and in patients who successfully retrieved sperm.
Article Synopsis
- * Research indicates that age is a significant factor in the success of TESE, with older patients (over 30) generally having lower sperm retrieval rates, while those younger than 20 show better outcomes similar to the 20-30 age range.
- * There is still a need for more studies to explore new markers to predict sperm retrieval success, especially considering the effects of age and androgen therapy, which has shown no clear impact on retrieval outcomes.